SUBJECT
Title
Introduction to biochemistry I.
Type of instruction
lecture
Level
master
Faculty
Part of degree program
Credits
3
Recommended in
Semester 3
Typically offered in
Autumn semester
Course description
Molecular bioenergetics. The structure of proteins. The function of enzymes - kinetics and energetics, enzyme mechanisms. Structural properties of nucleic acids. DNA “metabolism” - replication and repair. The molecular structure of the genetic information. Rearrangements in the genetic material. RNA metabolism - transcription, maturation and degradation. Protein metabolism - translation, post-translational modifications, transport and degradation. The regulation of enzyme quantities - regulation at the level of DNA, RNA and protein metabolism. Molecular systems biology - biological system information and molecular biotechnologies.
Readings
required readings:
- lecture slides
recommended readings:
- Stryer et al.: Biochemistry (W.H. Freeman, 2002)
- Lehninger et al.: Principles of Biochemistry (W.H. Freeman, 2008)