SUBJECT
Title
Quantitative models in cell and developmental biology
Type of instruction
lecture
Level
master
Faculty
Part of degree program
Credits
3
Recommended in
Semester 2
Typically offered in
Spring semester
Course description
The course covers mechanisms – and the corresponding mathematical or computational models – underlying various cell- and developmental biological phenomena. Topics: intercellular communication through ligand/receptor pairs, intracellular signal transduction networks, EGF and MAPK signaling, stochastic (Gillespie) reaction kinetics, transcriptional oscillators, feedbacks and robust adaptation, cell motility and multi-scale models of cellular systems.
Readings
required readings:
- figures, program codes and calculations are available at the course web page
recommended readings:
- Eric H Davidson: The regulatory genome, Academic Press 2006
- Hiraoki Kitano: Foundations of Systems Biology, MIT Press 2001