Chemistry of Organic Fluorine Compounds
History of fluorine compounds. Properties of fluorine and fluorine compounds. Nomenclature and spectroscopy. Effect of fluorine and fluorine containing substituents on reaction rates. Basic methods for the preparation of organofluorine compounds. Selective and exhaustive fluorinations. The role of fluorine in agrochemicals and pharmaceuticals. Fluorine chemistry and ‗performance chemicals‘. Introduction of 18F into PET diagnostics. Basics of fluorous biphasic catalysis and fluorous chemistry. Fluorophilicity, lipophilicity and molecular structure. Use of inorganic and organic fluorine compounds for organic syntheses.
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