SUBJECT

Introduction to Organosilicon Chemistry

lecture

Master

Faculty of Science

Chemistry MSc

2

Semester 2

Spring semester

Introduction of the Si atom into organic compounds and its influence on the physical and chemical properties thereof.The nature of the silicon-carbon and silicon-heteroatom bonds. General methods for the preparation of organosilicon compounds. The structure and reactivity of the main groups of organosilicon compounds. Preparation, structure investigation and characteristic reactions of reactive silicon compounds (silylenes and their derivatives). The chemistry of poly-silanes and -carbasilanes. The importance of the silicon substituted organic compounds in organic syntheses: the silyl group as blocking or activating group. Chemo-, regio- and stereoselective silylation methods. The use of organosilicon compounds in materials sciences, the importance of silsesquioxanes. Introduction to the bioorganosilicon chemistry, sila drugs.

Compulsory:

• N. N. Greenwood – A. Earnshaw: Chemistry of the elements (Pergamon Press, 1989)

• Elschenbroich – Salzer: Organometallics (Verlag Chemie, 1992)

Suggested:

• The Chemistry of Organic Silicon Compounds (eds Z. Rappoport, Y. Apeloig, John Wiley & Sons, 2001) 

• Comprehensive Organometallic Chemistry II: Silicon Group, Arsenic, Antimony and Bismuth (ed. A.G. Davies, Pergamon, 1995)

• Auner – Weis: Organosilicon Chemistry 5- From Molecules to Materials (John Wiley & Sons, 2003)