SUBJECT

Title

Medical Genomics

Type of instruction

lecture

Level

master

Part of degree program
Credits

2

Recommended in

Semesters 1-4

Typically offered in

Autumn/Spring semester

Course description

1. Basic genomics; Human genome;

2. General characteristics of multifactorial diseases;

3. Methods for the investigation of the genetic ground of multifactorial diseases;

4. Molecular pathomechanism of allergic asthma; Genomic ground of allergic asthma;

5. Molecular pathomechanism and genomic ground of type 1 diabetes mellitus;

6. Molecular pathomechanism and genomic ground of type 2 diabetes mellitus;

7. Molecular pathomechanism and genomic ground of obesitas;

8. Locusos, genes, gene variations behind obesity;

9. Molecular pathomechanism and genomic ground of hypertension;

10. Molecular pathomechanism and genomic ground of atherosclerosis;

11. Genomic ground of Alzheimer disease, Parkinson disease; psychogenomics

12. Role of gene-environmental interaction in the multifactorial diseases;

13. Examples from the pharmacogenomic results of the multifactorial diseases.

Readings
  • Strachan T, Read AP: Human Molecular Genetics 2; (also online through PubMed)

  • PubMed, Garland Science, 2004