SUBJECT

Title

Practical Course: NMR, Mass Spectroscopy and X-ray Diffraction

Type of instruction

practical

Level

Master

Part of degree program
Credits

6

Recommended in

Semester 2

Typically offered in

Spring semester

Course description

The aim of this course is the detailed study of experimental aspects of NMR spectroscopy, mass spectrometry and X-ray diffraction techniques, including the required data acquisition, processing steps and required computer software. At the end of this course the student will be able to plan, perform experiments as well as to treat and evaluate the acquired data on his/her own. The topics of this course covers the most important 1D and 2D, homo- and heteronuclear NMR experiments both in solutions and solid phase (DEPT, COSY, HSQC, HMBC, CPMAS, etc.). The aim of the X-ray diffraction exercises is the introduction to the practical steps of the structure determination of the small molecular and protein crystals, the visualization of molecules and the handling of international crystallographic databases.

Readings

Compulsory:

  • P.J. Hore: Nuclear Magnetic Resonance, Oxford University Press, 1995. (ISBN13: 9780198556824, ISBN10: 0198556829)

  • S. Berger, S. Braun: 200 and More NMR Experiments, Wiley-WCH, 2004. ISBN: 978-3-527-31067-8.

Suggested:

  • C. Giacovazzo, H.L. Monaco, G. Artioli, D. Viterbo, G. Ferraris, G. Gilli, G. Zanotti,

  • M.Catti: Fundamentals of Crystallography, IUCr/Oxford University Press, 2002