1. From the cistron to the complex gene.
2. Pedigree for Genetics,Genomics,Molecular Biology,Bioinformatics
3. Generalization of the allele concept, beyond the phenotypic variability, DNA polimorphysms, paralogy,orthology
4. Bacterium genetics: the partial diploid, linking DNA technology to classical bacterium genetics
5. Bacteriophage genetics : thinking in phage and diploids. Complementation, recombination, crossing over, gene conversion, genetic mapping. Phage genetics and DNA technology.
6. Plasmids, Transposons, phage genes : combinations and utilizations in the cloning aera.
7. Balanced lethality: complementation, balancer chromosomes, thoroughbred heterozygotes
8. Dissecting strutures and genetic pathways : epistases, suppression, inter-allelic complementation, phage and yeast di-hybrid set ups.
9. Gene silencing and phenocopy
10. Hybrid disgenesis, D.melanogaster, C.elegans, transposons P, Tc1, gene tagging, dominant-negative technique.
11. Bacteriophage lambda : the lambda paradigm for genetic regulation ,genetic switch, system biology, cooperative interactions, recruiting, link to developmental genetics
12. Tetrad analysis: gene conversion, crossing over, repair, half tetrad analysis, models for recombination.
13. The focus of mutation: gynander analysis , somatic crossing over –genetic mosaicism, blastoderma fate mapping in D.melanogaster.
14. Transgenic organisms: in genetic analyses, in bioindusrtry, agriculture, medicine
15. Historical genetics: mt genetics, Y chromosome genetics, hapmap
Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley „An introduction to genetic analysis”, 10th edition, W. H. Freeman, 2010
Anthony J.F. Griffiths: Modern Genetic Analysis, W. H. Freeman, 2002
A.H. Sturtevant: A History of Genetics, CSHL Press, 2001
hand-out printed materials from the lecturer