SUBJECT

Neuronal Cell Differentiation II

lecture

master

Faculty of Science

Biology MSc

2

Semesters 1-4

Autumn/Spring semester

1. Differentiation of the central nervous tissue I: morphology and molecular biology of the establishment of the neuroectoderm.

2. Regional differentiation of the central nervous tissue II: dorsoventral determination in the course of the neural tube formation

3. Regional Regional differentiation of the central nervous tissue III: the regional differentiation along the anterior – posterios body axes

4. Region-specific determination of the neurotransmitter phenotypes

5. The role of “neurotransmitter” substances in the neural tissue formation

6. Neurotransmitter receptors on developing neural cells

7. Development of the bioelectric properties during the formation of the neuronal phenotype I.: bioelectric properties of neural stem and progenitor cells

8. Development of the bioelectric properties during the formation of the neuronal phenotype II: voltage-dependent channels on developing neurons

9. Activity-dependent formation and elimination of morphologically / functionally distinct areas in the developing and mature neural tissue

10. Synaptic and neurite plasticity in the central nervous tissue

11. Regenerative capacity of the central nervous tissue

12. Neural stem cells; adulthood neurogenesis

13. Roles of glial cells in neuronal development and regeneration – an overview.

• Scott F. Gilbert: Developmental Biology; Palgrave Macmillan, 2003

• Bruce M. Carlson: Human Embryology and Developmental Biology, Elsevier Health Sciences, 2013, ISBN 9781455727940

• Hand-outs of the lectures